A reaction between an amide and LiAlH4 causes LiAlH4 to act as a __.

Disable ads (and more) with a premium pass for a one time $4.99 payment

Study for the MCAT Chemical and Physical Foundations of Biological Systems Exam. Practice with multiple choice questions, each with detailed explanations and hints. Excel in your exam and achieve your target score!

In the reaction between an amide and lithium aluminum hydride (LiAlH4), the critical role of LiAlH4 is that of a reducing agent. LiAlH4 is known for its strong reducing properties, particularly in the reduction of carbonyl compounds. An amide features a carbonyl group (C=O) directly bonded to a nitrogen, making it a suitable candidate for reduction.

During the reaction, LiAlH4 donates hydride ions (H-) to the carbonyl carbon of the amide. This process results in the conversion of the amide into an amine, indicating that the carbonyl group is reduced to a primary amine. This transformation exemplifies the reducing character of LiAlH4, as it reduces the oxidation state of the carbon atom in the amide.

While LiAlH4 can act as a base in other contexts due to its ability to deprotonate certain compounds, its primary role in the reaction with amides is that of a reducing agent. This highlights the importance of understanding the context of the reaction and the specific chemical behavior of the reagents involved.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy